The multiplier accelerator theory in the study of municipal-level investment

In our research we specially adapted the multiplier accelerator approach for analysis of investment processes on the municipal level. We analyzed the databases of municipalities of the Bashkortostan Republic and found a one-year lag and ratchet effects in the development of investment processes, which manifested themselves through steady rates of growth in the volumes of shipped goods and services in these areas while the amount of investment was declining. Excessively high values of the investment accelerator in certain municipalities were explained, on the one hand, by the insignificant changes in the economic performance of these municipalities and, on the other hand, by the inflow of capital, which was not related to the incentive function of return from the previous investment. The main causes of the disincentive function include the low investment attractiveness of the territories; the poorly developed environment for investment stimulation; the inefficiency of the investment itself; and its short-term character. Our approach combines the multiplier accelerator theory with the concept of efficient management of investment in socio-economic systems of various levels and thus it has enabled us to develop a matrix for diagnostics of investment processes by calculating investment efficiency (with the help of the investment multiplier) and the focus of the investment process (with the help of the investment accelerator). Upon these results we have mapped municipalities according to their levels of investment development and proposed a differentiated approach to managerial decision-making. These findings can be used to study investment attractiveness on the municipal level and to develop guidelines for assessment of investment attractiveness and for managerial decision-making to enhance investment efficiency

Intellectual сapital strategic management for regional innovative development

The article reveals the managerial aspects of the formation and use of the intellectual capital of the region, which have a strategic nature in the interests of its innovative development. The purpose of the work is to develop methodological recommendations for the management of intellectual capital in the interests of innovative developmen

Характеристика факторов риска у молодых людей с ранней ишемической болезнью сердца на фоне абдоминального ожирения

Aim. To assess the prevalence of cardiovascular risk factors in young adults aged 25-44 years with early coronary artery disease (CAD) and abdominal obesity (AO) in Novosibirsk.Methods. A random sample of subjects aged 25-44 years residing Novosibirsk underwent population screening. 1,457 people were examined (653 men and 804 women). The epidemiological diagnosis of CAD was established based on the validated epidemiological (according to the Rose Angina Questionnaire) and clinical (ECG decoded according to the Minnesota code) criteria. Early CAD was detected in 49 people who then were assigned into 4 subgroups: 1) obese subjects with CAD -24 people, 2) non-obese subjects with CAD - 25 people, 3) age- and sex-matched obese controls without CAD - 44 people, 4) age- and sex-matched non-obese controls without CAD - 30 people. The prevalence of the following CVD risk factors was assessed: smoking, increased body mass index (BMI), increased waist circumference (WC), the presence of arterial hypertension (AH), physical inactivity, elevated levels of low-density lipoprotein cholesterol (LDL-C), nonhigh density lipoprotein cholesterol (non-HDL-C), triglycerides (TG) in blood.Results. BMI, LDL-C and non-HDL-C increase 1.3-fold in obese subjects with CAD along with 1.9-fold increase in TG levels as compared to non-obese subjects with CAD. Obese men with CAD had BMI, non-HDL-C, and TG levels 1.3, 1.5, and 2.6 times higher respectively, compared with non-obese men with CAD. BMI, LDL-C levels, non-HDL-C levels and the presence of AH increased 5.2-, 1.6-, 1.6-, and 4.7-fold, respectively, in obese subjects with CAD compared with non-obese subjects with CAD. Obese men with CAD reported a 4.4- and 6.2-fold increase in the prevalence of increased BMI and the presence of AH, respectively, than non-obese men with CAD. The examined individuals revealed an independent direct association of the relative risk of CAD as a comorbidity of AH (OR = 3.368, CI 1.057-10.728, p = 0.040). In addition, men demonstrated an association with elevated levels of LDL-C (OR = 1.019, CI 1.000-1.039, p = 0.049) and non-HDL-C (OR = 1.019, CI 1.000-1.038, p = 0.049) in blood.Conclusion. AH, elevated levels of LDL-C, non-HDL-C and TG are considered as significant risk factors in obese people under 45 years of age (mainly in men) with early CAD.Цель. Изучить характеристику факторов риска сердечно-сосудистых заболеваний у людей 25-44 лет, проживающих в Новосибирске, с ранней ишемической болезнью сердца (ИБС), определенной по стандартизованным эпидемиологическим критериям, на фоне абдоминального ожирения (АО).Материалы и методы. Проведен одномоментный популяционный скрининг случайной выборки населения Новосибирска в возрасте 25-44 лет. Обследовано 1 457 человек: 653 мужчины и 804 женщины. Эпидемиологический диагноз «ишемическая болезнь сердца» установлен согласно валидизированным эпидемиологическим (кардиологический опросник Роуза) и клинико-функциональным (запись электрокардиографии с расшифровкой по Миннесотскому коду) критериям. Ранняя ИБС выявлена у 49 человек. Сформированы четыре подгруппы обследованных: 1-я - лица с ИБС на фоне АО (n = 24), 2-я - лица с ИБС без АО (n = 25), 3-я - контрольные по возрасту и полу лица без ИБС с АО (n = 44), 4-я - контрольные по возрасту и полу лица без ИБС и АО (n = 30). Оценены факторы риска сердечно-сосудистых заболеваний: курение, повышенный индекс массы тела (ИМТ), наличие артериальной гипертензии (АГ), увеличенная окружность талии, сниженная физическая активность, повышенные уровни в крови холестерина липопротеинов низкой плотности (ЛНП-ХС), холестерина, не связанного с липопротеинами высокой плотности (не-ЛВП-ХС), триглицеридов (ТГ).Результаты. У лиц с ИБС на фоне АО показатели ИМТ, ЛНП-ХС и не-ЛВП-ХС выше в 1,3 раза, а показатель ТГ - в 1,9 раза в сравнении с лицами с ИБС без АО. У мужчин с ИБС на фоне АО показатели ИМТ, не-ЛВП-ХС и ТГ выше в 1,3, 1,5 и 2,6 раза соответственно в сравнении с мужчинами с ИБС без АО. У лиц с ИБС на фоне АО распространенность повышенных ИМТ, уровней ЛНП-ХС, не-ЛВП-ХС и наличия АГ выше в 5,2, 1,6, 1,6 и 4,7 раза соответственно в сравнении с лицами с ИБС без АО. У мужчин с ИБС на фоне АО распространенность повышенного ИМТ и наличия АГ выше в 4,4 и 6,2 раза соответственно в сравнении с мужчинами с ИБС без АО. У обследованных лиц выявлена независимая прямая ассоциация относительного риска развития ИБС с наличием АГ (отношение шансов, ОШ, 3,368; 95% доверительный интервал, ДИ, 1,057-10,728; р = 0,040), а у мужчин - с повышенными уровнями в крови ЛНП-ХС (ОШ 1,019; ДИ 1,000-1,039; р = 0,049) и не-ЛВП-ХС (ОШ 1,019; ДИ 1,000-1,038; р = 0,049).Заключение. У лиц с ранней ИБС (в возрасте до 45 лет), преимущественно у мужчин, развившейся в том числе на фоне абдоминального ожирения, значимыми факторами риска являются АГ и повышенные уровни в крови ЛНП-ХС, не-ЛВП-ХС, ТГ

The effect of the solutions of whey and growth stimulators on productivity and quality of spring wheat grain

Increasing of productivity and grain quality of spring wheat under conditions of Republic of Mari El is one of the main tasks of agricultural science and practice. In decision of this task an important role belongs to growth regulators as they can stimulate growth and development of plants, increase resistance to stressful growing conditions being used in extremely low concentrations. The use of milk whey solution at different concentrations was studied experimentally in the Republic of Mari El for the first time. At the first stage of research the optimal concentration of milk whey solution positively influencing on grain yield of spring wheat was determined. The highest yield was in the variants with application of the solution in the ratio whey : water - 2:10 and 3:10. The increase to the control was significant - 0.38.0.39 t/ha. At the second stage it was studied the effect of milk whey solutions and growth stimulators Planriz and Zircon on the photosynthesis activity of crops, yield and grain quality of spring wheat. It was revealed that treatment of crops with whey solutions increases photosynthetic capacity and net photosynthetic productivity in the period of stem elongation - earing respectively on 131.0-138.8 thousand m2/ha x day and 2.0-2.4 g/m2 x day. Use of solutions of milk whey and growth regulators provides a significant increasing of grain yield. Thus use of milk whey solutions was more effective. The increase in yield was 0.33-0.35 t/ha. The use of whey solutions has greatly improved technological properties of grain: it increases the grain protein content by 1.6. 1.8 %, of gluten - by 1.0-1.1% and hardness - by 5.0-7.2%

Strategic directions of foreign trade activity of the forest industry of Russia

The most complete realization of the export potential of the Russian forest industry on the world market provides for the implementation of a strategic scenario for the development of the industry. The article analyzes the reality of achieving forecast indicators of priority areas for non&resource export of forest products. To stimulate investment in timber production, the authors proposed the use of a special investment contract mechanism, which has already found application in other sectors of Russian industry

ESG-Transformation of Business Processes

Современная повестка ESG-трансформации стала затрагивать все больше сфер российской экономики. Относительное новое понятие только приобретает популярность у российских компаний и уже активно встраивается в деятельность как на корпоративном уровне больших корпораций, так и на уровне малых предприятий. Тем или иным по масштабу организациям присуще формирование бизнес-процессов в условиях устойчивого развития, как одной из основных функций управления для получения желаемого результата. ESG-трансформация бизнес-процессов предполагает рассмотреть бизнес-процесс со стороны устойчивого развития, и встроить эту повестку в уже имеющуюся на предприятии систему управления.The modern ESG transformation agenda has begun to affect more and more areas of the Russian economy. A relatively new concept is only gaining popularity among Russian companies and is already being actively integrated into the activities both at the corporate level of large corporations and at the level of small enterprises.Organizations of one or another scale are characterized by the formation of business processes in the conditions of sustainable development, as one of the main management functions to obtain the desired result. ESG-transformation of business processes involves considering the business process from the perspective of sustainable development, and embedding this agenda into the management system already in place at the enterprise

Modern Challenges to Sustainable Development

In the article examines contemporary sustainable development challenges for PJSC «Gazprom» and its subsidiary LLC «Gazprom Transgaz Ufa», as a leading enterprise in the oil and gas complex of Russia and the Republic of Bashkortostan. Today, PJSC «Gazprom» is facing global changes in the political, economic, technological and environmental spheres, which directly or indirectly affect the effectiveness of the implementation of the sustainable development goals that were formed in the Long-term Development Program of PJSC «Gazprom» until 2025.В статье рассматриваются современные вызовы устойчивого развития для ПАО «Газпром» и его дочернего общества ООО «Газпром трансгаз Уфа», как для ведущего предприятия нефтегазового комплекса России и Республики Башкортостан. Сегодня ПАО «Газпром» сталкивается с глобальными мировыми изменениями в политических, экономических, технологических и экологических сферах, которые прямо или косвенно отражаются на эффективности реализации поставленных задач в области устойчивого развития, которые были сформированы в Долгосрочной программе развития ПАО «Газпром» до 2025 года

The association of ecg TV1>TV6 phenomenon as electrophysiological sign of metabolic myocardial disorders with risk factors for ischemic heart disease in the population of 25–44 years

The aim of the study was to study the associations of electrophysiological signs of metabolic disorders the myocardium (ECG phenomenon TV1>TV6 and components of the ECG of the of left ventricular hypertrophy phenomenon) with some lipid and non-lipid risk factors in an urban population of 25–44 years. Material and methods. A population survey of a random sample of the population aged 25–44 years (1439 people, 656 men, 783 women) in Novosibirsk was conducted. Blood concentrations of total cholesterol, high (HDL-C) and low density lipoprotein cholesterol (LDL-C), and triglycerides were measured. Systolic and diastolic blood pressure, body mass index, waist circumference, presence of arterial hypertension, smoking status were evaluated. The following ECG markers were analyzed: ECG phenomenon TV1>TV6 (the amplitude of T in V1 exceeds the amplitude of T in V6), components of the ECG of the of left ventricular hypertrophy phenomenon. Results. ECG phenomenon TV1>TV6 was detected in 0.8 % of people (1.4 % of men, 0.2 % of women). In the general population among people with ECG phenomenon TV1>TV6, persons with triglyceride levels >150 mg/dl, with an increased body mass index/waist circumference, with arterial hypertension are 3.0, 2.0, 2.3 and 3.5 times more, respectively, than among people without ECG phenomenon TV1>TV6. Among men with ECG phenomenon TV1>TV6, persons with elevated triglyceride levels, with an increased body mass index/waist circumference, with arterial hypertension are 2.2, 1.5, 2.5 and 2.8 times more, respectively, than among men without ECG phenomenon TV1>TV6. The components of the ECG of the of left ventricular hypertrophy phenomenon were found in 1.4 % of people (2.1 % of men, 0.9 % of women). In the general population, among people with elevated triglyceride levels, with arterial hypertension, as well as in smokers – individuals with signs of left ventricular hypertrophy are 2.3, 2.1 and 1.7 times more, respectively, than without them. Among men with elevated blood levels of LDL-C, non-HDL-C, as well as smokers-individuals with components of the ECG of the of left ventricular hypertrophy phenomenon are 1.4, 1.4 and 1.6 times more, respectively. Conclusions. ECG phenomenon TV1>TV6 and components of the ECG of the of left ventricular hypertrophy phenomenon are associated with lipid and non-lipid risk factors for cardiovascular diseases, which indicates a potentiating effect of metabolic disorders in the body not only on the development of risk factors for cardiovascular diseases, but also metabolic disorders of the myocardium

Prevalence of coronary heart disease (by epidemiological criteria) and its association with lipid and non-lipid risk factors in the Novosibirsk population of 25-45 years

Aim. To study the prevalence of coronary artery disease (CAD) according to epidemiological criteria in the Novosibirsk population of 25-45 years, to identify its associations with lipid and non-lipid risk factors.Material and methods. Cross-sectional survey of the Novosibirsk population aged 25-45 was carried out. The study included 650 people (268 men and 382 women). The epidemiological diagnosis of CAD (“Certain CAD” — CCAD, “Possible CHD” — PCAD) was made according to epidemiological (according to Rose questionnaire) and clinical functional (ECG recording with the Minnesota code) criteria. Blood levels of total cholesterol, triglycerides, cholesterol of low and high density lipoproteins (LDL-Ch, HDL-Ch) were determined. Blood pressure were measured (SBP, DBP), the presence of arterial hypertension (AH), body mass index and the smoking status were assessed.Results. CCAD was detected in 3,8% people, including in 2,6% men and in 4,7% women. PCAD was detected in 6,1% people, including 78% men and 5,0% women. The results of univariate analysis showed that the relative risk of PCAD in the population is higher in people with low HDL-Ch (OR 2,136), in smokers (OR 1,925) and in AH subjects (OR 2,235). The results of logistic regression analysis showed that the relative risk of PCHD in the population, independently of other factors, is associated with lower level of HDL-Ch (OR 0,180) and higher SBP (OR 1,026). The relative risk of CCAD developing in the female population is higher in women with low HDL-Ch (OR 3,800) and in AH women (OR 4,572).Conclusion. In the Novosibirsk population of 25-45 years, CAD, determined by epidemiological criteria, independently of lipid and non-lipid risk factors, is associated with AH presence and reduced HDL-Ch

Right chambers of the heart in children with pulmonary circulation hypervolemia

The ultrasound and angiographic parameters of the right chambers of the heart were analyzed in children with pulmonary arterial hypertension (PAH) associated with congenital heart defects. The investigation was conducted in relation to the functional class (degree) of PAH. Right cardiac remodeling was found to depend to a greater extent on afterload (pulmonary artery systolic pressure and pulmonary vascular resistance); moreover, diastolic dysfunction developed just in moderate (Functional Class II) PAH. It was ascertained that there was a prompter development of PAH with myocardial systolic and diastolic dysfunction in the presence of congenital malformations with arterial hypoxemia